Female survivors of childhood, adolescent, and young adult cancers are at risk of impaired sexual functioning. Cancer and cancer treatment may alter normal sexual development and predispose women to sexual problems through both physiologic and psychosocial mechanisms. Sexual problems are classified as sexual dysfunction disorders when they meet the criteria of the Diagnostic and Statistical Manual of Mental Disorders, 5th edition (DSM-5), and cause significant distress. There are a number of effective treatments for female sexual dysfunction, though few have been rigorously evaluated in women with a history of cancer. By recognizing sexual health as a pertinent survivorship issue and through regular screening, healthcare providers can play an important role in optimizing sexual well-being in this patient population.

Terri L. Woodard

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