The outcome of localized osteosarcoma has remained constant over the past 30 years. Histological response to preoperative chemotherapy is the best predictor of outcome. Strategies to alter treatment based on histological response have not resulted in increased survival.

Authors: R. Venkatramani, J. Murray, L. Helman, W. Meyer, M.J. Hicks, R. Krance, C. Lau, E. Jo, M. Chintagumpala

Read more